Rakesh K. Singh, B. Pharm., PhD

Rakesh K. Singh, B. Pharm., PhD
Assistant Professor of Pharmacology

7000 Chad Colley Blvd
Fort Smith, AR  72916

I received my bachelor’s degree in pharmaceutical sciences from the Birla Institute of Technology in Ranchi, India and then completed my PhD in Pharmacology from the University of Kansas in 2008.

My graduate work was centered on investigating the involvement of the serotonin 2A receptor in the pharmacological activity of atypical antipsychotics such as olanzapine, where I identified the important interaction between the serotonin receptor and JAK/STAT pathway.  My post-doctoral work at the University of Illinois at Chicago, was focused on investigating the role of G s alpha protein in the therapeutic lag associated with antidepressants like SSRIs.  I also had the pleasure of teaching Cardiovascular lectures in Prematriculation Physiology classes during the summers of 2009 & 2010 while at UIC.  I then conducted research on the biochemical interactions responsible for increasing the pharmacological activity of methotrexate in the absence of NAMPT protein while working at the University of Kansas Medical Center.

My research experience has been heavily focused on understanding the biochemical interactions among various cellular pathways that regulate the pharmacological activity of numerous drugs.  My future research interest includes understanding the role of the JAK/STAT pathway in the anti-inflammatory activity of methotrexate.